Immunohistochemistry in Cancer Diagnosis: A Review

Abstract

Immunohistochemistry in cancer diagnosis holds great potenƟal to improve paƟent’s outcomes through enhanced diagnosƟc accuracy and more effecƟve treatment strategies. AnƟgen-anƟbody interacƟons is one of its main objecƟves that uƟlizes the specific binding of anƟbodies to cellular anƟ- gens allowing for the precise idenƟficaƟon and localizaƟon of specific proteins within Ɵssue samples. However, there exist pracƟcal hitches in the form of Ɵssue fixaƟon, epi- tope retrieval, and anƟbody quality. It is crucial to conƟnue streamlining the techniques and scoring systems to guar- antee their reliability in various contexts. Understanding the interactions is pivotal for the accurate diagnosis, prog- nosis, and future perspectives. As technology continues to advance and our understanding of cancer biology deep- ens, immunohistochemistry will remain an invaluable tool for precision in cancer diagnosis.