Abstract:
Immunohistochemistry in cancer diagnosis holds great
potenƟal to improve paƟent’s outcomes through enhanced
diagnosƟc accuracy and more effecƟve treatment strategies.
AnƟgen-anƟbody interacƟons is one of its main objecƟves
that uƟlizes the specific binding of anƟbodies to cellular anƟ-
gens allowing for the precise idenƟficaƟon and localizaƟon
of specific proteins within Ɵssue samples. However, there
exist pracƟcal hitches in the form of Ɵssue fixaƟon, epi-
tope retrieval, and anƟbody quality. It is crucial to conƟnue
streamlining the techniques and scoring systems to guar-
antee their reliability in various contexts. Understanding
the interactions is pivotal for the accurate diagnosis, prog-
nosis, and future perspectives. As technology continues
to advance and our understanding of cancer biology deep-
ens, immunohistochemistry will remain an invaluable tool
for precision in cancer diagnosis.
